Publications
Goodnough CL, Montoya J, Cartusciello EB, Floranda EL, Gross ER. Nicotinamide adenine dinucleotide supplementation fails to enhance anesthetic recovery in rodents. Sci Rep. 2025 Jan 9, PMID: 39789056; PMCID: PMC11718248.
Rwere F, White JR, Hell RCR, Yu X, Zeng X, McNeil L, Zhou KN, Angst MS, Chen CH, Mochly-Rosen D, Gross ER. Uncovering newly identified aldehyde dehydrogenase 2 genetic variants that lead to acetaldehyde accumulation after an alcohol challenge. J Transl Med. 2024 Jul 29, PMID: 39075523; PMCID: PMC11288122.
Moh I, Simon D, Gross ER. The Alcohol Flush Response. Graph Med Rev. 2024, Epub 2024 Feb 22. PMID: 38895023; PMCID: PMC11185044.
Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao MT, Ameen M, Zhang M, Gross ER, Qi LS, Sayed N, Wu JC. Statins improve endothelial function via suppression of epigenetic-driven EndMT. Nat Cardiovasc Res. 2023 May, Epub 2023 May 8. PMID: 37693816; PMCID: PMC10489108.
Guo H, Yu X, Liu Y, Paik DT, Justesen JM, Chandy M, Jahng JWS, Zhang T, Wu W, Rwere F, Zhao SR, Pokhrel S, Shivnaraine RV, Mukherjee S, Simon DJ, Manhas A, Zhang A, Chen CH, Rivas MA, Gross ER, Mochly-Rosen D, Wu JC. SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant. Sci Transl Med. 2023 Jan 25, Epub 2023 Jan 25. PMID: 36696485; PMCID: PMC10297796.
He S, Zambelli VO, Sinharoy P, Brabenec L, Bian Y, Rwere F, Hell RC, Stein Neto B, Hung B, Yu X, Zhao M, Luo Z, Wu C, Xu L, Svensson KJ, McAllister SL, Stary CM, Wagner NM, Zhang Y, Gross ER. A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents. J Clin Invest. 2023 Feb 1, PMID: 36472910; PMCID: PMC9888391.
Le AD, Li Y, Zhu A, Singh J, Xu JY, Srinivasan M, Palaniappan LP, Long J, Gross ER. Effect of race on opioid drug overdose deaths in the United States: an observational cross-sectional study. Br J Anaesth. 2022 Sep, Epub 2022 Jul 2. PMID: 35787800; PMCID: PMC9583734.
Yu X, Zeng X, Xiao F, Chen R, Sinharoy P, Gross ER. E-cigarette aerosol elevates cardiovascular oxidative stress in mice with aldehyde dehydrogenase-2 deficiency. Redox Biology, 2022, Aug 54:102369 PMID: 35751982
Zambelli VO, Alcantara Q, Gross ER. Alcohol and analgesia: a fine wine getting better with age. British Journal of Anaesthesia, 2021 June, PMID: 34090680
McAllister SL, Sinharoy P, Vasu M, Gross ER. Aberrant reactive aldehyde detoxification by aldehyde dehydrogenase-2 influences endometriosis development and pain-associated behaviors. Pain 2021 Jan;162(1):71-83. PMID: 32541390
Wu Y, Chen AW, Goodnough CL, Lu Y, Zhang Y, Gross ER. IcyHot analgesic topical cream limits cardiac injury in rodents. Translational Research, 2021 227: 42-52 PMID: 32629175
Otto M, Bucher C, Liu W, Müller M, Schmidt T, Kardell M, Driessen MN, Rossaint J, Gross ER, Wagner N. 12(S)-HETE mediates diabetes induced endothelial dysfunction by activating intracellular endothelial cell TRPV1. Journal of Clinical Investigation, 2020 Aug 17:136621 PMID: 32584793
Jiang S, Bastov D, Bharadwaj A, Gross ER. Asian Flush. Annals of Intern Medicine, 2019 Aug 13. doi: 10.7326/G18-0025. PMID: 31404928
Chen CH, Ferriera JCB, Mochly-Rosen D, Gross ER. Alcohol consumption and vascular disease: other points to consider. Lancet, 2019 Nov 2;394 (10209):1617-1618. PMID: 31690444
Wagner NM, Lu Y, Gross ER. Remote Ischemic Preconditioning and Cardiac Surgery. New England Journal of Medicine, 374(5):490, 2016.
Gross ER, Zambelli VO, Chen C, Mochly-Rosen D. A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant. Annual Review of Pharmacology and Toxicology. 55:107-27, 2015.
Zambelli VO*, Gross ER*, Chen CH, Guttierrez V, Cury Y, Mochly-Rosen D. Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain. Science Translational Medicine, 27:6(251):251ra118, 2014.
Gross ER, Hsu AK, Gross GJ. Opioid-induced acute cardioprotection occurs by glycogen synthase kinase inhibition. Circulation Research, 94(7): 960-6, 2004.
Gross ER, Gare M, Toller WG, Kersten JR, Warltier DC, Pagel PS. Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs. Anesthesia & Analgesia. 92(2):299-305, 2001.